NPC1L1-dependent transport of 27-alkyne cholesterol in intestinal epithelial cells

Niemann-Pick C1 Like-1 (NPC1L1) mediates the uptake of micellar cholesterol by intestinal epithelial cells and is the molecular target of the cholesterol-lowering drug ezetimibe (EZE). The detailed mechanisms responsible for intracellular shuttling of micellar cholesterol are not fully understood du...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Ticho, Alexander L., Calzadilla, Nathan, Malhotra, Pooja, Lee, Hyunjin, Anbazhagan, Arivarasu Natarajan, Saksena, Seema, Dudeja, Pradeep K., Lee, Daesung, Gill, Ravinder K., Alrefai, Waddah A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163569/
https://ncbi.nlm.nih.gov/pubmed/33760662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00062.2021
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