5′-AMP-activated Protein Kinase (AMPK) Supports the Growth of Aggressive Experimental Human Breast Cancer Tumors

Rapid tumor growth can establish metabolically stressed microenvironments that activate 5′-AMP-activated protein kinase (AMPK), a ubiquitous regulator of ATP homeostasis. Previously, we investigated the importance of AMPK for the growth of experimental tumors prepared from HRAS-transformed mouse emb...

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Hlavní autoři: Laderoute, Keith R., Calaoagan, Joy M., Chao, Wan-ru, Dinh, Dominc, Denko, Nicholas, Duellman, Sarah, Kalra, Jessica, Liu, Xiaohe, Papandreou, Ioanna, Sambucetti, Lidia, Boros, Laszlo G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132788/
https://ncbi.nlm.nih.gov/pubmed/24993821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576371
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