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5′-AMP-Activated Protein Kinase (AMPK) Activity Is Elevated Early During Primary Brain Tumor Development In the Rat
We found that adenosine 5′-monophosphate-activated protein kinase (AMPK)—which is considered the “fuel sensor” of mammalian cells because it directly responds to the depletion of the fuel molecule ATP—is strongly activated by tumor-like hypoxia and glucose deprivation. We also observed abundant AMPK...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992079/ https://ncbi.nlm.nih.gov/pubmed/20635388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25558 |
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