DNA Damage to a Single Chromosome End Delays Anaphase Onset

Chromosome ends contain nucleoprotein structures known as telomeres. Damage to chromosome ends during interphase elicits a DNA damage response (DDR) resulting in cell cycle arrest. However, little is known regarding the signaling from damaged chromosome ends (designated here as “TIPs”) during mitosi...

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Main Authors: Silva, Bárbara Alcaraz, Stambaugh, Jessica R., Yokomori, Kyoko, Shah, Jagesh V., Berns, Michael W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
DNA and Chromosomes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132783/
https://ncbi.nlm.nih.gov/pubmed/24982423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.535955
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