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Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregation

Microtubules of the mitotic spindle are the basis for chromosome segregation. In metaphase, microtubules show high dynamic instability, thought to aid the ‘search and capture’ of chromosomes for bipolar alignment on the spindle. At anaphase onset microtubules suddenly become more stable, but it is u...

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Detalhes bibliográficos
Main Authors: Higuchi, Toru, Uhlmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586334/
https://ncbi.nlm.nih.gov/pubmed/15650742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03240
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