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Targeting telomere-containing chromosome ends with a near-infrared femtosecond laser to study the activation of the DNA damage response and DNA damage repair pathways

Telomeres are at the ends of chromosomes. Previous evidence suggests that laser-induced deoxyribose nucleic acid (DNA) breaks at chromosome ends during anaphase results in delayed cytokinesis. A possible explanation for this delay is that the DNA damage response (DDR) mechanism has been activated. W...

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Detalles Bibliográficos
Main Authors: Silva, Bárbara Alcaraz, Stambaugh, Jessica R., Berns, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado: Society of Photo-Optical Instrumentation Engineers 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782557/
https://ncbi.nlm.nih.gov/pubmed/24064949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.18.9.095003
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