FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers

Genetic recombination is important for generating diversity and to ensure faithful segregation of chromosomes at meiosis. However, few crossovers (COs) are formed per meiosis despite an excess of DNA double-strand break precursors. This reflects the existence of active mechanisms that limit CO forma...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Girard, Chloe, Crismani, Wayne, Froger, Nicole, Mazel, Julien, Lemhemdi, Afef, Horlow, Christine, Mercier, Raphael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132730/
https://ncbi.nlm.nih.gov/pubmed/25038251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku614
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky