FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers

Genetic recombination is important for generating diversity and to ensure faithful segregation of chromosomes at meiosis. However, few crossovers (COs) are formed per meiosis despite an excess of DNA double-strand break precursors. This reflects the existence of active mechanisms that limit CO forma...

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Detaylı Bibliyografya
Asıl Yazarlar: Girard, Chloe, Crismani, Wayne, Froger, Nicole, Mazel, Julien, Lemhemdi, Afef, Horlow, Christine, Mercier, Raphael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132730/
https://ncbi.nlm.nih.gov/pubmed/25038251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku614
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