FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers

Genetic recombination is important for generating diversity and to ensure faithful segregation of chromosomes at meiosis. However, few crossovers (COs) are formed per meiosis despite an excess of DNA double-strand break precursors. This reflects the existence of active mechanisms that limit CO forma...

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Bibliografski detalji
Glavni autori: Girard, Chloe, Crismani, Wayne, Froger, Nicole, Mazel, Julien, Lemhemdi, Afef, Horlow, Christine, Mercier, Raphael
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Genome Integrity, Repair and Replication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132730/
https://ncbi.nlm.nih.gov/pubmed/25038251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku614
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