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Molecular basis of nucleotide-dependent substrate engagement and remodeling by an AAA+ activator
Binding and hydrolysis of ATP is universally required by AAA+ proteins to underpin their mechano-chemical work. Here we explore the roles of the ATPase site in an AAA+ transcriptional activator protein, the phage shock protein F (PspF), by specifically altering the Walker B motif sequence required i...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132715/ https://ncbi.nlm.nih.gov/pubmed/25063294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku588 |
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