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A dual switch controls bacterial enhancer-dependent transcription

Bacterial RNA polymerases (RNAPs) are targets for antibiotics. Myxopyronin binds to the RNAP switch regions to block structural rearrangements needed for formation of open promoter complexes. Bacterial RNAPs containing the major variant σ(54) factor are activated by enhancer-binding proteins (bEBPs)...

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Detalles Bibliográficos
Main Authors: Wiesler, Simone C., Burrows, Patricia C., Buck, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505966/
https://ncbi.nlm.nih.gov/pubmed/22965125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks844
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