ATPase Site Architecture Is Required for Self-Assembly and Remodeling Activity of a Hexameric AAA+ Transcriptional Activator

AAA+ proteins (ATPases associated with various cellular activities) are oligomeric ATPases that use ATP hydrolysis to remodel their substrates. By similarity with GTPases, a dynamic organization of the nucleotide-binding pockets between ATPase protomers is proposed to regulate functionality. Using t...

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Detaylı Bibliyografya
Asıl Yazarlar: Joly, Nicolas, Zhang, Nan, Buck, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2012
Konular:
Short Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419264/
https://ncbi.nlm.nih.gov/pubmed/22789710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.06.012
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