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Phenotype profile of a genetic mouse model for Muenke syndrome

PURPOSE: The Muenke syndrome mutation (FGFR3(P250R)), which was discovered 15 years ago, represents the single most common craniosynostosis mutation. Muenke syndrome is characterized by coronal suture synostosis, mid-face hypoplasia, subtle limb anomalies, and hearing loss. However, the spectrum of...

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Bibliografiske detaljer
Main Authors: Nah, Hyun-Duck, Koyama, Eiki, Agochukwu, Nneamaka B., Bartlett, Scott P., Muenke, Maximilian
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131982/
https://ncbi.nlm.nih.gov/pubmed/22872265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00381-012-1778-9
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