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The Tau Mutation of Casein Kinase 1ϵ Sets the Period of the Mammalian Pacemaker via Regulation of Period1 or Period2 Clock Proteins
The suprachiasmatic nucleus (SCN) of the hypothalamus is the principal circadian pacemaker in mammals, coordinating daily metabolic and physiological rhythms with the cycle of sleep and wakefulness. SCN neurons define circadian time via an auto-regulatory feedback loop in which the activation of Per...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131702/ https://ncbi.nlm.nih.gov/pubmed/24682205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730414520663 |
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