Tuning the Period of the Mammalian Circadian Clock: Additive and Independent Effects of CK1ε(Tau) and Fbxl3(Afh) Mutations on Mouse Circadian Behavior and Molecular Pacemaking

Circadian pacemaking in the suprachiasmatic nucleus (SCN) revolves around a transcriptional/posttranslational feedback loop in which period (Per) and cryptochrome (Cry) genes are negatively regulated by their protein products. Genetically specified differences in this oscillator underlie sleep and m...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Maywood, Elizabeth S., Chesham, Johanna E., Meng, Qing-Jun, Nolan, Patrick M., Loudon, Andrew S. I., Hastings, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623629/
https://ncbi.nlm.nih.gov/pubmed/21273438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4107-10.2011
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