Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

Loss of noradrenergic locus coeruleus (LC) neurons is a prominent feature of aging–related neurodegenerative diseases, like Parkinson’s disease (PD). The basis of this vulnerability is not understood. To explore possible physiological determinants, LC neurons were studied using electrophysiological...

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Autori principali: Sanchez–Padilla, J., Guzman, J.N., Ilijic, E., Kondapalli, J., Galtieri, D.J., Yang, B., Schieber, S., Oertel, W., Wokosin, D., Schumacker, P. T., Surmeier, D. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131291/
https://ncbi.nlm.nih.gov/pubmed/24816140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3717
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