Chloride channel blockers promote relaxation of TEA-induced contraction in airway smooth muscle

Enhanced airway smooth muscle (ASM) contraction is an important component in the pathophysiology of asthma. We have shown that ligand gated chloride channels modulate ASM contractile tone during the maintenance phase of an induced contraction, however the role of chloride flux in depolarization-indu...

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Autores principales: Yim, Peter D., Gallos, George, Perez-zoghbi, Jose F., Trice, Jacquelyn, Zhang, Yi, Siviski, Matthew, Sonett, Joshua, Emala, Charles W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Japan Society of Smooth Muscle Research 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131261/
https://ncbi.nlm.nih.gov/pubmed/24662476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.49.112
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