Chloride channel blockers promote relaxation of TEA-induced contraction in airway smooth muscle

Enhanced airway smooth muscle (ASM) contraction is an important component in the pathophysiology of asthma. We have shown that ligand gated chloride channels modulate ASM contractile tone during the maintenance phase of an induced contraction, however the role of chloride flux in depolarization-indu...

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Main Authors: Yim, Peter D., Gallos, George, Perez-zoghbi, Jose F., Trice, Jacquelyn, Zhang, Yi, Siviski, Matthew, Sonett, Joshua, Emala, Charles W.
Formato: Artigo
Idioma:Inglês
Publicado: Japan Society of Smooth Muscle Research 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131261/
https://ncbi.nlm.nih.gov/pubmed/24662476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.49.112
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