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Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists
Severe bronchospasm refractory to β-agonists continues to cause significant morbidity and mortality in asthmatic patients. We questioned whether chloride channels/transporters are novel targets for the relaxation of airway smooth muscle (ASM). We have screened a library of compounds, derivatives of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121642/ https://ncbi.nlm.nih.gov/pubmed/24879056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00351.2013 |
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