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Influence of a dual-injection regimen, plerixafor, and CXCR4 on in-utero hematopoietic stem cell transplantation and engraftment using the sheep model
BACKGROUND: Inadequate engraftment of hematopoietic stem cells (HSCs) following in-utero HSC transplantation (IUHSCT) remains a major obstacle for the prenatal correction of numerous hereditary disorders. HSCs express CXCR4 receptors that allow homing and engraftment in response to SDF1 ligand prese...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131210/ https://ncbi.nlm.nih.gov/pubmed/25108653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2014.05.025 |
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