Human embryonic stem cell–derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients

The human/sheep xenograft model has proven valuable in assessing the in vivo hematopoietic activity of stem cells from a variety of fetal and postnatal human sources. CD34(+)/lineage(-) or CD34(+)/CD38(-) cells isolated from human embryonic stem cells (hESCs) differentiated on S17 feeder layer were...

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Main Authors: Narayan, A. Daisy, Chase, Jessica L., Lewis, Rachel L., Tian, Xinghui, Kaufman, Dan S., Thomson, James A., Zanjani, Esmail D.
Formato: Artigo
Idioma:Inglês
Publicado: © 2006 by The American Society of Hematology 2006
Assuntos:
Stem Cells in Hematology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895718/
https://ncbi.nlm.nih.gov/pubmed/16278307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-1922
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