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Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation

In utero hematopoietic stem/progenitor cell transplantation (IUHSCT) has only been fully successful in the treatment of congenital immunodeficiency diseases. Using sheep as a large animal model of IUHSCT, we demonstrate that administration of CD146(+)CXCL12(+)VEGFR2(+) or CD146(+)CXCL12(+)VEGFR2(−)...

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Publicado en:Stem Cell Reports
Main Authors: Mokhtari, Saloomeh, Colletti, Evan J., Atala, Anthony, Zanjani, Esmail D., Porada, Christopher D., Almeida-Porada, Graça
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912311/
https://ncbi.nlm.nih.gov/pubmed/27304918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.05.009
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