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Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland
Mesenchymal dysplasia (mes) mice harbour a truncation in the C-terminal region of the Hh-ligand receptor, Patched-1 (mPtch1). While the mes variant of mPtch1 binds to Hh-ligands with an affinity similar to that of wild type mPtch1 and appears to normally regulate canonical Hh-signalling via smoothen...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131199/ https://ncbi.nlm.nih.gov/pubmed/24769368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.04.007 |
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