A carregar...

Distinct Effects of the mesenchymal dysplasia Gene Variant of Murine Patched-1 Protein on Canonical and Non-canonical Hedgehog Signaling Pathways

Hedgehog (Hh) signaling requires regulation of the receptor Patched-1 (Ptch1), which, in turn, regulates Smoothened activity (canonical Hh signaling) as well as other non-canonical signaling pathways. The mutant Ptch1 allele mesenchymal dysplasia (mes), which truncates the Ptch1 C terminus, produces...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Harvey, Malcolm C., Fleet, Andrew, Okolowsky, Nadia, Hamel, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036205/
https://ncbi.nlm.nih.gov/pubmed/24570001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514844
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!