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The power comparison of the haplotype-based collapsing tests and the variant-based collapsing tests for detecting rare variants in pedigrees

BACKGROUND: Both common and rare genetic variants have been shown to contribute to the etiology of complex diseases. Recent genome-wide association studies (GWAS) have successfully investigated how common variants contribute to the genetic factors associated with common human diseases. However, unde...

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Autori principali: Guo, Wei, Shugart, Yin Yao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131059/
https://ncbi.nlm.nih.gov/pubmed/25070353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-632
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