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The power comparison of the haplotype-based collapsing tests and the variant-based collapsing tests for detecting rare variants in pedigrees
BACKGROUND: Both common and rare genetic variants have been shown to contribute to the etiology of complex diseases. Recent genome-wide association studies (GWAS) have successfully investigated how common variants contribute to the genetic factors associated with common human diseases. However, unde...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131059/ https://ncbi.nlm.nih.gov/pubmed/25070353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-632 |
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