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Comparison of haplotype-based tests for detecting gene–environment interactions with rare variants

Dissecting the genetic mechanism underlying a complex disease hinges on discovering gene–environment interactions (GXE). However, detecting GXE is a challenging problem especially when the genetic variants under study are rare. Haplotype-based tests have several advantages over the so-called collaps...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Papachristou, Charalampos, Biswas, Swati
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299304/
https://ncbi.nlm.nih.gov/pubmed/31329820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbz031
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