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Weighted pedigree-based statistics for testing the association of rare variants

BACKGROUND: With the advent of next-generation sequencing (NGS) technologies, researchers are now generating a deluge of data on high dimensional genomic variations, whose analysis is likely to reveal rare variants involved in the complex etiology of disease. Standing in the way of such discoveries,...

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Hlavní autoři: Shugart, Yin Yao, Zhu, Yun, Guo, Wei, Xiong, Momiao
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827928/
https://ncbi.nlm.nih.gov/pubmed/23176082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-667
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