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A novel statistical method for rare-variant association studies in general pedigrees
Both population-based and family-based designs are commonly used in genetic association studies to identify rare variants that underlie complex diseases. For any type of study design, the statistical power will be improved if rare variants can be enriched in the samples. Family-based designs, with a...
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Publicado no: | BMC Proc |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5133499/ https://ncbi.nlm.nih.gov/pubmed/27980635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0029-6 |
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