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A novel statistical method for rare-variant association studies in general pedigrees

Both population-based and family-based designs are commonly used in genetic association studies to identify rare variants that underlie complex diseases. For any type of study design, the statistical power will be improved if rare variants can be enriched in the samples. Family-based designs, with a...

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Bibliografske podrobnosti
izdano v:BMC Proc
Main Authors: Zhu, Huanhuan, Wang, Zhenchuan, Wang, Xuexia, Sha, Qiuying
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133499/
https://ncbi.nlm.nih.gov/pubmed/27980635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0029-6
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