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Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor

In previous studies we demonstrated that the tumor-promoting agent 12-O-tetradecanoyl phorbol 13-acetate (TPA) and related macrocyclic diterpenes are potent inhibitors of the binding of epidermal growth factor (EGF) to its cell surface receptors in HeLa cells. The present study explores the specific...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, Lih-Syng, Weinstein, I. Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1979
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC413101/
https://ncbi.nlm.nih.gov/pubmed/315558
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