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Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor

In previous studies we demonstrated that the tumor-promoting agent 12-O-tetradecanoyl phorbol 13-acetate (TPA) and related macrocyclic diterpenes are potent inhibitors of the binding of epidermal growth factor (EGF) to its cell surface receptors in HeLa cells. The present study explores the specific...

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Autors principals: Lee, Lih-Syng, Weinstein, I. Bernard
Format: Artigo
Idioma:Inglês
Publicat: 1979
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC413101/
https://ncbi.nlm.nih.gov/pubmed/315558
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