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Local Delivery of Gemcitabine Inhibits Pancreatic and Cholangiocarcinoma Tumor Growth by Promoting Epidermal Growth Factor Receptor Degradation

Gemcitabine is clinically used to treat certain types of cancers, including pancreatic and biliary cancer. We investigated the signal transduction pathways underlying the local antitumor effects of gemcitabine-eluting membranes (GEMs) implanted in pancreatic/biliary tumor-bearing nude mice. Here, we...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Jang, Sung Ill, Fang, Sungsoon, Baek, Yi-Yong, Lee, Don Haeng, Na, Kun, Lee, Su Yeon, Lee, Dong Ki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084314/
https://ncbi.nlm.nih.gov/pubmed/32111094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051605
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