Local Delivery of Gemcitabine Inhibits Pancreatic and Cholangiocarcinoma Tumor Growth by Promoting Epidermal Growth Factor Receptor Degradation

Gemcitabine is clinically used to treat certain types of cancers, including pancreatic and biliary cancer. We investigated the signal transduction pathways underlying the local antitumor effects of gemcitabine-eluting membranes (GEMs) implanted in pancreatic/biliary tumor-bearing nude mice. Here, we...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Jang, Sung Ill, Fang, Sungsoon, Baek, Yi-Yong, Lee, Don Haeng, Na, Kun, Lee, Su Yeon, Lee, Dong Ki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084314/
https://ncbi.nlm.nih.gov/pubmed/32111094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051605
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