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Local Delivery of Gemcitabine Inhibits Pancreatic and Cholangiocarcinoma Tumor Growth by Promoting Epidermal Growth Factor Receptor Degradation

Gemcitabine is clinically used to treat certain types of cancers, including pancreatic and biliary cancer. We investigated the signal transduction pathways underlying the local antitumor effects of gemcitabine-eluting membranes (GEMs) implanted in pancreatic/biliary tumor-bearing nude mice. Here, we...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Jang, Sung Ill, Fang, Sungsoon, Baek, Yi-Yong, Lee, Don Haeng, Na, Kun, Lee, Su Yeon, Lee, Dong Ki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084314/
https://ncbi.nlm.nih.gov/pubmed/32111094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051605
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