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Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor

In previous studies we demonstrated that the tumor-promoting agent 12-O-tetradecanoyl phorbol 13-acetate (TPA) and related macrocyclic diterpenes are potent inhibitors of the binding of epidermal growth factor (EGF) to its cell surface receptors in HeLa cells. The present study explores the specific...

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Detalhes bibliográficos
Main Authors: Lee, Lih-Syng, Weinstein, I. Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413101/
https://ncbi.nlm.nih.gov/pubmed/315558
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