Systematic Identification of Barriers to Human iPSC Generation

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerative medicine, but the underlying mechanisms remain poorly understood. We report a systematic dissection of human cellular reprogramming by combining a genome-wide RNAi screen, innovative comp...

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Autors principals: Qin, Han, Diaz, Aaron, Blouin, Laure, Lebbink, Robert Jan, Patena, Weronika, Tanbun, Priscilia, LeProust, Emily M., McManus, Michael T., Song, Jun S., Ramalho-Santos, Miguel
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130998/
https://ncbi.nlm.nih.gov/pubmed/25036638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.040
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