Systematic Identification of Barriers to Human iPSC Generation

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerative medicine, but the underlying mechanisms remain poorly understood. We report a systematic dissection of human cellular reprogramming by combining a genome-wide RNAi screen, innovative comp...

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Bibliografiska uppgifter
Huvudupphovsmän: Qin, Han, Diaz, Aaron, Blouin, Laure, Lebbink, Robert Jan, Patena, Weronika, Tanbun, Priscilia, LeProust, Emily M., McManus, Michael T., Song, Jun S., Ramalho-Santos, Miguel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130998/
https://ncbi.nlm.nih.gov/pubmed/25036638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.040
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