Systematic Identification of Barriers to Human iPSC Generation

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerative medicine, but the underlying mechanisms remain poorly understood. We report a systematic dissection of human cellular reprogramming by combining a genome-wide RNAi screen, innovative comp...

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Hlavní autoři: Qin, Han, Diaz, Aaron, Blouin, Laure, Lebbink, Robert Jan, Patena, Weronika, Tanbun, Priscilia, LeProust, Emily M., McManus, Michael T., Song, Jun S., Ramalho-Santos, Miguel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130998/
https://ncbi.nlm.nih.gov/pubmed/25036638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.040
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