Systematic Identification of Barriers to Human iPSC Generation

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerative medicine, but the underlying mechanisms remain poorly understood. We report a systematic dissection of human cellular reprogramming by combining a genome-wide RNAi screen, innovative comp...

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Bibliographische Detailangaben
Hauptverfasser: Qin, Han, Diaz, Aaron, Blouin, Laure, Lebbink, Robert Jan, Patena, Weronika, Tanbun, Priscilia, LeProust, Emily M., McManus, Michael T., Song, Jun S., Ramalho-Santos, Miguel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130998/
https://ncbi.nlm.nih.gov/pubmed/25036638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.040
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