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Essential role for mevalonate synthesis in DNA replication
The relationship between 3-hydroxy-3-methylglutaryl (HMG) CoA reductase activity [mevalonate:NADP(+) oxidoreductase (CoA-acylating), EC 1.1.1.34] and DNA synthesis was studied in synchronized cultures of BHK-21 cells. During a 24-hr period of cell replication, two phases of accelerated thymidine inc...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1979
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/291922/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.10.5056 |
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