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Isopentenyladenine as a mediator of mevalonate-regulated DNA replication.

The mechanism by which the cholesterol precursor, mevalonate, regulates S-phase DNA replication was examined in synchronized BHK cells. As previously demonstrated by this laboratory, blocking 3-hydroxy-3-methylglutaryl-CoA reductase [mevalonate:NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34] with...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Huneeus, V Q, Wiley, M H, Siperstein, M D
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1980
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6934516/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.5842
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