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A Comparison of Methods for Measuring Rectal HIV Levels Suggests that HIV DNA Resides in Cells other than CD4+T Cells, Including Myeloid Cells

We compared different techniques for measuring gut HIV reservoirs and assessed for HIV in non-CD4+T cells. HIV DNA levels were similar when measured from rectal biopsies and isolated rectal cells, while HIV RNA tended to be higher in rectal cells. HIV DNA levels in total rectal cells were greater th...

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Main Authors: Yukl, Steven A., Sinclair, Elizabeth, Somsouk, Ma, Hunt, Peter W., Epling, Lorrie, Killian, Maudi, Girling, Valerie, Li, Peilin, Havlir, Diane V., Deeks, Steven G., Wong, Joseph K., Hatano, Hiroyu
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130176/
https://ncbi.nlm.nih.gov/pubmed/24322272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000166
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