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The Distribution of HIV DNA and RNA in Cell Subsets Differs in Gut and Blood of HIV-Positive Patients on ART: Implications for Viral Persistence

Even with optimal antiretroviral therapy, human immunodeficiency virus (HIV) persists in plasma, blood cells, and tissues. To develop new therapies, it is essential to know what cell types harbor residual HIV. We measured levels of HIV DNA, RNA, and RNA/DNA ratios in sorted subsets of CD4(+) T cells...

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Main Authors: Yukl, Steven A., Shergill, Amandeep K., Ho, Terence, Killian, Maudi, Girling, Valerie, Epling, Lorrie, Li, Peilin, Wong, Lisa K., Crouch, Pierre, Deeks, Steven G., Havlir, Diane V., McQuaid, Kenneth, Sinclair, Elizabeth, Wong, Joseph K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778964/
https://ncbi.nlm.nih.gov/pubmed/23852128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit308
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