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Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells

Increased expressions of fatty acid synthase (FASN) and epidermal growth factor receptor (EGFR) are common in cancer cells. De novo synthesis of palmitate by FASN is critical for the survival of cancer cells via mechanisms independent of its role as an energy substrate. Besides the plasma membrane a...

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Detalhes bibliográficos
Main Authors: Bollu, Lakshmi Reddy, Ren, Jiangong, Blessing, Alicia Marie, Katreddy, Rajasekhara Reddy, Gao, Guang, Xu, Lei, Wang, Jinrong, Su, Fei, Weihua, Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128886/
https://ncbi.nlm.nih.gov/pubmed/25483192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29338
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