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Genome-Wide Modulation of Gene Transcription in Ovarian Carcinoma Cells by a New Mithramycin Analogue

Ovarian cancer has a poor prognosis due to intrinsic or acquired resistance to some cytotoxic drugs, raising the interest in new DNA-binding agents such as mithramycin analogues as potential chemotherapeutic agents in gynecological cancer. Using a genome-wide approach, we have analyzed gene expressi...

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Détails bibliographiques
Auteurs principaux: Vizcaíno, Carolina, Núñez, Luz-Elena, Morís, Francisco, Portugal, José
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128730/
https://ncbi.nlm.nih.gov/pubmed/25110883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104687
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