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Contribution of Human Immunodeficiency Virus Type 1 Minority Variants to Reduced Drug Susceptibility in Patients on an Integrase Strand Transfer Inhibitor-Based Therapy

The role of HIV-1 minority variants on transmission, pathogenesis, and virologic failure to antiretroviral regimens has been explored; however, most studies of low-level HIV-1 drug-resistant variants have focused in single target regions. Here we used a novel HIV-1 genotypic assay based on deep sequ...

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Detalhes bibliográficos
Main Authors: Gibson, Richard M., Weber, Jan, Winner, Dane, Miller, Michael D., Quiñones-Mateu, Miguel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128663/
https://ncbi.nlm.nih.gov/pubmed/25110880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104512
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