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Challenges in predicting the evolutionary maintenance of a phage transgene

BACKGROUND: In prior work, a phage engineered with a biofilm-degrading enzyme (dispersin B) cleared artificial, short-term biofilms more fully than the phage lacking the enzyme. An unresolved question is whether the transgene will be lost or maintained during phage growth – its loss would limit the...

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Autors principals: Schmerer, Matthew, Molineux, Ian J, Ally, Dilara, Tyerman, Jabus, Cecchini, Nicole, Bull, James J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128545/
https://ncbi.nlm.nih.gov/pubmed/25126112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-1611-8-21
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