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Experimental evolution of UV resistance in a phage

The dsDNA bacteriophage T7 was subjected to 30 cycles of lethal ultraviolet light (UV) exposure to select increased resistance to UV. The exposure effected a 0.9999 kill of the ancestral population, and survival of the ending population was nearly 50-fold improved. At the end point, a 2.1 kb deletio...

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Udgivet i:PeerJ
Main Authors: Tom, Eric F., Molineux, Ian J., Paff, Matthew L., Bull, James J.
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042481/
https://ncbi.nlm.nih.gov/pubmed/30013847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5190
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