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Evolutionary Stability of a Refactored Phage Genome

[Image: see text] Engineered genetic systems are commonly unstable; if propagated, they evolve to reverse or modify engineered elements because the elements impair fitness. A goal of synthetic biology is thus to anticipate and avoid detrimental engineering, but little is yet known about which types...

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Hlavní autoři: Springman, Rachael, Molineux, Ian J., Duong, Chanan, Bull, Robert J., Bull, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2012
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600784/
https://ncbi.nlm.nih.gov/pubmed/23519680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb300040v
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