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Evolutionary Stability of a Refactored Phage Genome
[Image: see text] Engineered genetic systems are commonly unstable; if propagated, they evolve to reverse or modify engineered elements because the elements impair fitness. A goal of synthetic biology is thus to anticipate and avoid detrimental engineering, but little is yet known about which types...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600784/ https://ncbi.nlm.nih.gov/pubmed/23519680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb300040v |
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