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Allosteric transition and binding of small molecule effectors causes curvature change in central β-sheets of selected enzymes
A quantitative description of allosteric transition remains a significant science challenge. Many allosteric enzymes contain a central β-sheet in their catalytic domain. When an allosteric protein undergoes the transition between T (tense) and R (relaxed) allosteric states, this central β-sheet unde...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127431/ https://ncbi.nlm.nih.gov/pubmed/20602244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-010-0784-7 |
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