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Competitive regulation of modular allosteric aptazymes by a small molecule and oligonucleotide effector
The hairpin ribozyme can catalyze the cleavage of RNA substrates by employing its conformational flexibility. To form a catalytic complex, the two domains A and B of the hairpin-ribozyme complex must interact with one another in a folding step called docking. We have constructed hairpin ribozyme var...
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Formato: | Artigo |
Idioma: | Inglês |
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Copyright 2005 by RNA Society
2005
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370835/ https://ncbi.nlm.nih.gov/pubmed/16199761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2840805 |
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