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Competitive regulation of modular allosteric aptazymes by a small molecule and oligonucleotide effector

The hairpin ribozyme can catalyze the cleavage of RNA substrates by employing its conformational flexibility. To form a catalytic complex, the two domains A and B of the hairpin-ribozyme complex must interact with one another in a folding step called docking. We have constructed hairpin ribozyme var...

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Detalhes bibliográficos
Main Authors: NAJAFI-SHOUSHTARI, S. HANI, FAMULOK, MICHAEL
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370835/
https://ncbi.nlm.nih.gov/pubmed/16199761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2840805
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