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Plasmin Regulation through Allosteric, Sulfated, Small Molecules
Plasmin, a key serine protease, plays a major role in clot lysis and extracellular matrix remodeling. Heparin, a natural polydisperse sulfated glycosaminoglycan, is known to allosterically modulate plasmin activity. No small allosteric inhibitor of plasmin has been discovered to date. We screened an...
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| Gepubliceerd in: | Molecules |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6272155/ https://ncbi.nlm.nih.gov/pubmed/25569517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20010608 |
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